The objective of the study is to understand the prospects offered by different systems for rapid and visual detection of phthalic contaminants present in cleanrooms, on-board instruments and satellites. These systems make it possible to detect the presence of contaminants by fluorescence, color change or other phenomenon from a critical threshold set at a surface contamination of 0.5 µg/cm². Fluoroscein, one of the most used fluorophore, was implemented in a filter paper to detecte vapor traces of diethylhexyl phthalate (DEHP). This presentation will describe general steps involved in the development of this system, its validation for DEHP vapor detection and a potential explanation for the sensing mechanism: photoinduced electron transfer, tautomerization or/and quenching.This will lead to rapid and visual detection of the presence of contaminants in real time for rapid decision-making (cleaning, installation of protection, etc.) thus causing anomalies in cleanroom.