The possibility of generating electrical power using photovoltaic solar panels remains a challenge for lunar bases today. The PV solution chosen must be as resistant as possible to the extremely harsh lunar environment and in particular to lunar dust. These particles have an irregular, elongated shape with sharp edges and an average size of 70 µm. They are porous, extremely adhesive, abrasive and electrostatically charged. Their effects on solar panels are varied: obscuration leading to power loss, surface contamination, and abrasion of the front surface, electrostatic discharge, and alteration of thermal properties. The aim of this work is to develop an original, accurate method for depositing lunar dust on a large surface, combined with optical and electrical evaluation of the photovoltaic Assemblies (PVA). Two main parameters were assessed: the relative short-circuit current to have access to the optical properties of the PV module, and the relative maximum power output to compare with the literature. The effects of a lunar soil simulant on the performances of a photovoltaic module are investigated experimentally, within laboratory conditions. PV modules are made with a Coverglass and 2 x ½ silicon solar cells and stick onto a thin honeycomb. The lunar dust simulant used is the lunar highland dust simulant from Exolith Lab. A first regime named “coating” associated with a linear decline and a second regime named “overlapping” associated with an exponential decline were identified in accordance with what suggested in literature. According to the model established from experiments, if a semi-annual or an annual cleaning would be planned, the associated power loss would be between ~0.5% - 2.5% or between ~1% - 5.5%, respectively. Results will be presented with more details, and will show that the developed method is a good way to test the impact of lunar cleaning systems on PVA.